Rizatriptan EP Impurity I HCl CAS 144034-84-4 (free base)
| CAS No. | 144034-84-4 (free base) |
| Molecular Formula | C14H17N5 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Rizatriptan EP Impurity I HCl (CAS 144034-84-4 (free base)), a pharmacopoeial impurity reference standard (molecular formula C14H17N5HCl, MW 291.78 g/mol) used for the identification and quantification of trace impurities in APIs.
Rizatriptan EP Impurity I HCl (C14H17N5HCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Rizatriptan EP Impurity I HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H17N5 HCl |
| Molecular Weight | 291.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Rizatriptan Standards
- Rizatriptan EP Impurity G (CAS 1000673-59-5)
- Rizatriptan Dimer Impurity 3 (CAS 1016900-25-6)
- Rizatriptan impurity 01 (CAS 1030849-63-8)
- Rizatriptan Impurity N8 (CAS 1034806-43-3)
- Rizatriptan Impurity 14 (CAS 110-95-2)
- Rizatriptan Impurity 4 (CAS 1135479-41-2)
- Rizatriptan Dimer (CAS 1135479-44-5)
- Rizatriptan Impurity 15 (CAS 114094-45-0)
Recommended Standards
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- N-Me-D-Val-OBzl.TosOH (CAS 2044710-41-8)
- 4-Cyclopentene-1,3-diol, monoacetate, (1s-tranS)- (9ci) (CAS 61348-01-4)
- Lidocaine Impurity 54 (CAS CATO-C4X-167954)
- 1-{2,5-dimethyl-1-[4-(morpholin-4-yl)phenyl]-1H-pyrrol-3-yl}-2-{1,4-dioxa-8-azaspiro[4.5]decan-8-yl}ethane-1,2-dione (CAS 866144-08-3)
- 4-Bromo-1-cyclopropylpyridin-2(1H)-one (CAS 1193334-86-9)
- N-Acetyl-D-glucosamine- (CAS 253679-94-6)
- Peptide Impurity 24 (CAS CATO-CPTD788824)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com